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Low Dose Dexamethasone Suppression Testing

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The Low Dose Dexamethasone Suppression Test is used to monitor evaluate patients for Hyperadrenocorticisim or “Cushing’s Disease”. This test involves tracking a patients blood cortisol level changes in response to an injection of a corticosteroid called dexametasone.

In the clinic we take a blood sample, then give an injection of a low dose of Dexamethasone. Another blood sample is taken 4 hours later and a final sample 4 hours after that. Typically the patient will need to stay with us for the 8 1/2 hours needed to complete the sample collection.

All three samples are sent together to our reference lab to be tested for cortisol levels, and we are then able to determine if the response in the patient is normal or not.

Please follow these instructions if your pet is scheduled for a Low Dose Dexamethasone Suppression Test:

1) You must be at the clinic at your scheduled time please, as we must start the test in time to collect all samples before closing.

2) You can feed and exercise your pet as usual prior to this test.

3) Expect to have to leave your pet for 8-9 hours.

For more information on the tests for Cushing’s disease, click here.

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